ASCO: Targeted Rx Slows Ovarian Ca Progression
CHICAGO -- Adding the oral anti-angiogenesis drug pazopanib (Votrient) to standard treatment extended disease-free survival in patients with advanced ovarian cancer by an average of 5.6 months, a phase III study showed.
The time to progression was a median of 17.9 months among women taking pazopanib versus 12.3 months for those in the placebo arm (HR 0.77; 95% CI 0.64-0.91, P=0.0021), according to Andreas du Bois, MD, a professor of gynecologic oncology at Kliniken Essen Mitte in Essen, Germany, and colleagues
"Our findings show that we finally have a drug that can maintain control over ovarian cancer growth achieved through initial treatments," du Bois said here at the American Society of Clinical Oncology meeting.
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